Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | CASP2 | P42575 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24884918 | 0.96 | MEN1 (0.71) | MEN1KMT2ARECQLEPHX1CASP2 | |
| SCHEMBL25466799 | 0.94 | MEN1 (0.68) | MEN1KMT2ARECQLEPHX1CASP2 | |
| SCHEMBL25090248 | 0.94 | MEN1 (0.68) | MEN1KMT2ARECQLEPHX1CASP2 | |
| SCHEMBL25466788 | 0.94 | MEN1 (0.68) | MEN1KMT2ARECQLEPHX1CASP2 | |
| SCHEMBL25921370 | 0.94 | MEN1 (0.68) | MEN1KMT2ARECQLEPHX1CASP2 | |
| SCHEMBL18677306 | 0.87 | MEN1 (0.56) | MEN1KMT2ARECQLEPHX1ALDH1A1 | |
| SCHEMBL10101148 | 0.84 | MEN1 (0.89) | MEN1KMT2ARECQLEPHX1CASP2 | |
| SCHEMBL14000019 | 0.84 | CASP2 (0.60) | MEN1KMT2AEPHX1CASP2NAAA | |
| SCHEMBL25466986 | 0.83 | MEN1 (0.59) | MEN1KMT2ARECQLEPHX1CASP2 | |
| SCHEMBL22837715 | 0.83 | MEN1 (0.53) | MEN1KMT2ARECQLEPHX1CASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009061448-A9 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF PROTEINURIC DISEASES | THE GENERAL HOSPITAL CORPORATION (US) | 2009-08-13 | — | — | WO | disclosed |