Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.81 |
| ▸ | TUBB1 | Q9H4B7 | 10/20 | 0.69 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.67 |
| ▸ | TUBB | P07437 | 3/20 | 0.67 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.67 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.67 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.67 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.67 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.67 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.67 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.67 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.67 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.67 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.67 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.67 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.67 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.67 |
| ▸ | NQO1 | P15559 | 1/20 | 0.67 |
| ▸ | NQO2 | P16083 | 1/20 | 0.67 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30940360 | 0.90 | APP (0.93) | APPTUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL1486816 | 0.90 | APP (0.93) | APPTUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL30502377 | 0.90 | APP (0.93) | APPTUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL3390342 | 0.90 | APP (1.00) | APPTUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL1486818 | 0.90 | APP (0.93) | APPTUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL31271176 | 0.90 | APP (0.93) | APPTUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL13322133 | 0.87 | TTR (0.81) | APPALOX5CYP1A1PTGS1PTGS2 | |
| SCHEMBL28445854 | 0.84 | ALOX5 (0.88) | APPTUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL28444241 | 0.84 | ALOX5 (0.88) | APPTUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL12305067 | 0.83 | LCK (0.75) | APPALOX5NQO2TTRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230172947-A1 | METHODS AND COMPOSITIONS FOR TREATING ENDOMETRIAL CANCER | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-06-08 | — | — | US | disclosed |
| WO-2020113373-A1 | METHOD OF TREATING AGE-RELATED MACULAR DEGENERATION | ZHUHAI QIWEI BIO-TECHNOLOGY LTD. (CN) | 2020-06-11 | — | — | WO | disclosed |
| WO-2020113759-A1 | METHOD OF TREATING AGE-RELATED MACULAR DEGENERATION | ZHUHAI QIWEI BIO-TECHNOLOGY LTD. (CN) | 2020-06-11 | — | — | WO | disclosed |
| WO-2020098630-A1 | ANIMAL MODELS, SCREENING METHODS, AND TREATMENT METHODS FOR INTRAOCULAR DISEASES OR DISORDERS | ZHUHAI QIWEI BIO-TECHNOLOGY LTD. (CN) | 2020-05-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230172947-A1 | METHODS AND COMPOSITIONS FOR TREATING ENDOMETRIAL CANCER | HSD17B11, CYP19A1, NR5A1 | APP 4815/4885TUBB1 580/4885TUBB4A 504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.