Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
| ▸ | TPMT | P51580 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16652911 | 0.83 | KDM4E (0.44) | TTRKDM4EMAOBTPMT | |
| SCHEMBL16750946 | 0.83 | SMN1; SMN2 (0.40) | TTRSMN1; SMN2POLBNLRP3CYP3A4 | |
| SCHEMBL879358 | 0.82 | TTR (0.46) | TTRSMN1; SMN2POLBNLRP3CYP3A4 | |
| SCHEMBL22991362 | 0.78 | TTR (0.61) | TTRSMN1; SMN2POLBNLRP3KDM4E | |
| SCHEMBL24506701 | 0.78 | TP53 (0.43) | TTRSMN1; SMN2POLBNLRP3HDAC3 | |
| SCHEMBL15368352 | 0.74 | SMN1; SMN2 (0.40) | TTRSMN1; SMN2POLBNLRP3CYP3A4 | |
| SCHEMBL2261818 | 0.72 | TTR (0.56) | TTRERN1 | |
| SCHEMBL10498088 | 0.72 | TTR (0.50) | TTRSMN1; SMN2POLBNLRP3CYP3A4 | |
| SCHEMBL24195885 | 0.71 | PTPRC (0.39) | TTRSMN1; SMN2POLBNLRP3CYP3A4 | |
| SCHEMBL28879905 | 0.71 | TTR (0.39) | TTRSMN1; SMN2POLBNLRP3CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020099190-A1 | POLYMER FOR LIQUID EMBOLIC AGENTS AND METHOD OF OBTAINING SAME | LVD BIOTECH S. L. (ES) | 2020-05-22 | — | — | WO | disclosed |