Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
| ▸ | TPMT | P51580 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15368352 | 0.82 | SMN1; SMN2 (0.40) | TTRPOLBNLRP3TPMTSMN1; SMN2 | |
| SCHEMBL22991362 | 0.82 | TTR (0.61) | TTRPOLBNLRP3SMN1; SMN2ERN1 | |
| SCHEMBL22014369 | 0.82 | TTR (0.42) | TTRPOLBNLRP3TPMTHDAC3 | |
| 2,3,5-Triiodobenzoic Acid SCHEMBL39041 | 0.81 | TPMT (0.50) | TTRPOLBNLRP3TPMTHDAC3 | |
| SCHEMBL12966232 | 0.79 | HDAC3 (0.41) | TTRPOLBNLRP3TPMTHDAC3 | |
| SCHEMBL22991599 | 0.79 | TTR (0.50) | TTRPOLBNLRP3HDAC3HDAC4 | |
| SCHEMBL29367522 | 0.79 | TTR (0.39) | TTRPOLBNLRP3TPMTHDAC3 | |
| 2,3,5-Triiodobenzoic Acid SCHEMBL23524593 | 0.79 | TPMT (0.48) | TTRPOLBNLRP3TPMTHDAC3 | |
| SCHEMBL879357 | 0.79 | TTR (0.39) | TTRPOLBNLRP3TPMTHDAC3 | |
| SCHEMBL29595299 | 0.79 | HDAC3 (0.41) | TTRPOLBNLRP3TPMTHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023140231-A1 | RESIST COMPOSITION, METHOD FOR FORMING RESIST PATTERN, AND COMPOUND | 東京応化工業株式会社 | 2023-07-27 | — | — | WO | disclosed |
| WO-2020228627-A1 | NOVEL BIMODAL SMALL MOLECULE CONTRAST AGENT AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 南京鼓楼医院 | 2020-11-19 | — | — | WO | disclosed |
| US-8574550-B2 | Biocompatible polymeric contrast agents and radiopaque materials for medical services | CORDIS CORPORATION | 2013-11-05 | — | — | US | disclosed |
| US-8197796-B2 | organic high intensity X-ray contrast agents, dispersed within or conjugated biodegradable polymers, suitable for enhancing the imaging of medical devices, particularly polymeric medical devices and polymeric coatings | CORDIS CORPORATION | 2012-06-12 | — | — | US | disclosed |
| EP-1815871-B1 | Radiographic contrasting agents and radio-opaque polymeric materials for medical devices | CORDIS CORP (US) | 2012-03-28 | — | — | EP | disclosed |
| US-7771705-B2 | Radiographic contrasting agents and radio-opaque polymeric materials for medical devices | CORDIS CORPORATION (US) | 2010-08-10 | — | — | US | disclosed |
| US-7704488-B2 | Dendritic and star-shaped contrast agents for medical devices and bioabsorbable radiopaque bulk material and method for producing same | CORDIS CORPORATION (US) | 2010-04-27 | — | — | US | disclosed |
| US-20090209745-A1 | RADIOGRAPHIC CONTRASTING AGENTS AND RADIO-OPAQUE POLYMERIC MATERIALS FOR MEDICAL DEVICES | CORDIS US CORP | 2009-08-20 | — | — | US | disclosed |
| US-20080275210-A1 | BIOCOMPATIBLE POLYMERIC CONTRAST AGENTS AND RADIOPAQUE MATERIALS FOR MEDICAL DEVICES | CORDIS US CORP | 2008-11-06 | — | — | US | disclosed |
| US-20080177102-A1 | DENDRITIC AND STAR-SHAPED CONTRAST AGENTS FOR MEDICAL DEVICES AND BIOABSORBABLE RADIOPAQUE BULK MATERIAL AND METHOD FOR PRODUCING SAME | CORDIS US CORP | 2008-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080177102-A1 | DENDRITIC AND STAR-SHAPED CONTRAST AGENTS FOR MEDICAL DEVICES AND BIOABSORBABLE RADIOPAQUE BULK MATERIAL AND METHOD FOR PRODUCING SAME | MSR1, MYD88, CD209 | TTR 4695/4885POLB 2721/4885NLRP3 1908/4885 |
| US-20090209745-A1 | RADIOGRAPHIC CONTRASTING AGENTS AND RADIO-OPAQUE POLYMERIC MATERIALS FOR MEDICAL DEVICES | MYADM, PBRM1, RXFP3 | TTR 2900/4885POLB 3268/4885NLRP3 653/4885 |
| US-20080275210-A1 | BIOCOMPATIBLE POLYMERIC CONTRAST AGENTS AND RADIOPAQUE MATERIALS FOR MEDICAL DEVICES | CD68, TLR9, PBRM1 | TTR 4506/4885POLB 1886/4885NLRP3 2063/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.