Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | GSR | P00390 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20698692 | 0.87 | NLRP3 (0.42) | NLRP3HSP90AA1GSR | |
| SCHEMBL25067006 | 0.84 | NLRP3 (0.44) | NLRP3HSP90AA1GSR | |
| SCHEMBL20698686 | 0.82 | NLRP3 (0.42) | NLRP3HSP90AA1GSR | |
| SCHEMBL22014583 | 0.82 | NLRP3 (0.42) | NLRP3HSP90AA1GSR | |
| SCHEMBL20698687 | 0.82 | NLRP3 (0.42) | NLRP3HSP90AA1GSR | |
| SCHEMBL22014416 | 0.82 | NLRP3 (0.42) | NLRP3HSP90AA1GSR | |
| SCHEMBL20698694 | 0.81 | NLRP3 (0.50) | NLRP3HSP90AA1 | |
| SCHEMBL25066943 | 0.81 | NLRP3 (0.39) | NLRP3 | |
| SCHEMBL20699061 | 0.80 | NLRP3 (0.46) | NLRP3HSP90AA1GSR | |
| SCHEMBL20698839 | 0.80 | NLRP3 (0.41) | NLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102574-A1 | THE COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS INFLAMMASOME RESEARCH, INC. (US) | 2020-05-22 | — | — | WO | disclosed |