Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 1/20 | 0.34 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.34 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.34 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | ALB | P02768 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19507327 | 0.83 | TTR (0.41) | GABRA1CYP2A6GABRB1MEN1TTR | |
| SCHEMBL22014711 | 0.83 | HTT (0.38) | ABCC9ABCC8KCNJ11KCNJ8CYP2A6 | |
| SCHEMBL1174938 | 0.77 | MEN1 (0.36) | ABCC9ABCC8KCNJ11KCNJ8GABRA1 | |
| SCHEMBL22705097 | 0.76 | CYP2A6 (0.39) | GABRA1CYP2A6GABRB1MEN1TTR | |
| SCHEMBL22705144 | 0.76 | ABCC9 (0.37) | ABCC9ABCC8KCNJ11KCNJ8CYP2A6 | |
| SCHEMBL14163825 | 0.75 | CYP2A6 (0.44) | ABCC9ABCC8KCNJ11KCNJ8CYP2A6 | |
| SCHEMBL14498168 | 0.75 | CYP2A6 (0.44) | ABCC9ABCC8KCNJ11KCNJ8CYP2A6 | |
| SCHEMBL25139005 | 0.74 | ABCC9 (0.32) | ABCC9ABCC8KCNJ11KCNJ8CYP2A6 | |
| SCHEMBL22014709 | 0.74 | ABCC9 (0.32) | ABCC9ABCC8KCNJ11KCNJ8CYP2A6 | |
| SCHEMBL21962157 | 0.73 | PTGDR2 (0.35) | ABCC9ABCC8KCNJ11KCNJ8GPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102574-A1 | THE COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS INFLAMMASOME RESEARCH, INC. (US) | 2020-05-22 | — | — | WO | disclosed |