Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16727214 | 0.85 | TP53 (0.42) | TP53THRBNPC1KMT2ALMNA | |
| Sulfuric Acid SCHEMBL9796519 | 0.83 | TP53 (0.60) | TP53THRBNPC1KMT2ALMNA | |
| SCHEMBL14065374 | 0.81 | LMNA (0.47) | TP53NPC1KMT2ALMNAPOLB | |
| SCHEMBL18538056 | 0.77 | TP53 (0.38) | TP53THRBNPC1KMT2A | |
| SCHEMBL16727200 | 0.77 | TP53 (0.42) | TP53THRBNPC1KMT2ADAO | |
| SCHEMBL15680239 | 0.76 | TP53 (0.40) | TP53THRBNPC1KMT2A | |
| SCHEMBL16093580 | 0.76 | KDM4E (0.45) | LMNA | |
| SCHEMBL18508820 | 0.75 | TP53 (0.50) | TP53THRBNPC1KMT2ALMNA | |
| SCHEMBL436410 | 0.73 | TP53 (0.49) | TP53THRBKMT2ALMNAPOLB | |
| SCHEMBL11266325 | 0.70 | HPGD (0.38) | TP53NPC1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020099858-A1 | CEPHALOSPORIN CIPROFLOXACIN HYBRID COMPOUNDS | IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY AND MEDICINE (GB) | 2020-05-22 | — | — | WO | disclosed |