Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.46 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.38 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 7/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 7/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22015371 | 0.77 | NR1H2 (0.50) | SMN1; SMN2AOC3 | |
| SCHEMBL25967035 | 0.71 | AOC3 (0.45) | AOC3HCRTR1HCRTR2 | |
| SCHEMBL18711481 | 0.69 | USP2 (0.53) | MEN1KMT2ACHRNB2CHRNA3CHRNA4 | |
| SCHEMBL29144277 | 0.69 | CHRNB2 (0.58) | SMN1; SMN2CHRNB2CHRNA3CHRNA4CHRNB4 | |
| SCHEMBL14873797 | 0.69 | CHRNB2 (0.58) | SMN1; SMN2CHRNB2CHRNA3CHRNA4CHRNB4 | |
| SCHEMBL23714408 | 0.69 | CHRNB2 (0.58) | SMN1; SMN2CHRNB2CHRNA3CHRNA4CHRNB4 | |
| SCHEMBL18685434 | 0.69 | CHRNB2 (0.58) | SMN1; SMN2CHRNB2CHRNA3CHRNA4CHRNB4 | |
| SCHEMBL14471289 | 0.69 | CHRNB2 (0.58) | SMN1; SMN2CHRNB2CHRNA3CHRNA4CHRNB4 | |
| SCHEMBL19456200 | 0.68 | — | — | |
| SCHEMBL14970378 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020099886-A1 | LOX INHIBITORS | THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) | 2020-05-22 | — | — | WO | disclosed |