Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HBB | P68871 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22014825 | 0.88 | SMN1; SMN2 (0.38) | SMN1; SMN2MEN1KMT2ALMNAGAA | |
| SCHEMBL22014827 | 0.88 | KMT2A (0.46) | SMN1; SMN2MEN1KMT2ALMNACHRM1 | |
| SCHEMBL22014820 | 0.83 | ACACB (0.40) | SMN1; SMN2MAPT | |
| SCHEMBL22014834 | 0.81 | KMT2A (0.30) | KMT2A | |
| SCHEMBL22014824 | 0.79 | CHRM1 (0.36) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL24209303 | 0.78 | CYP1A2 (0.39) | RAB9ANPC1HDAC1HDAC2SMN1; SMN2 | |
| SCHEMBL22014822 | 0.73 | NPC1 (0.48) | RAB9ANPC1KMT2ALMNAGAA | |
| SCHEMBL25389906 | 0.72 | NOTUM (0.51) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL25390551 | 0.72 | NOTUM (0.51) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL17134643 | 0.72 | NOTUM (0.51) | RAB9ANPC1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020099886-A1 | LOX INHIBITORS | THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) | 2020-05-22 | — | — | WO | disclosed |