Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22014346 | 0.76 | NLRP3 (0.32) | NLRP3 | |
| SCHEMBL22015594 | 0.76 | NLRP3 (0.36) | NLRP3 | |
| SCHEMBL22014420 | 0.75 | NLRP3 (0.31) | NLRP3 | |
| SCHEMBL22015607 | 0.70 | HSP90AA1 (0.33) | — | |
| SCHEMBL29687381 | 0.69 | KDM4E (0.32) | — | |
| SCHEMBL22014721 | 0.69 | — | — | |
| SCHEMBL21962221 | 0.69 | KDM4E (0.32) | — | |
| SCHEMBL23319827 | 0.68 | — | — | |
| SCHEMBL25066982 | 0.66 | NLRP3 (0.36) | NLRP3 | |
| SCHEMBL22015606 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102574-A1 | THE COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS INFLAMMASOME RESEARCH, INC. (US) | 2020-05-22 | — | — | WO | disclosed |