Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.45 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.38 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.38 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22015084 | 0.89 | TDP1 (0.54) | TDP1MAPK1MAPTPOLBPKM | |
| SCHEMBL22015083 | 0.89 | TDP1 (0.54) | TDP1MAPK1MAPTPOLBPKM | |
| SCHEMBL22015244 | 0.89 | MAPT (0.35) | TDP1MAPK1MAPTPOLBPKM | |
| SCHEMBL11542385 | 0.71 | TDP1 (0.73) | TDP1MAPK1MAPTPOLBPKM | |
| SCHEMBL11793832 | 0.71 | TDP1 (0.73) | TDP1MAPK1MAPTPOLBPKM | |
| SCHEMBL11793841 | 0.71 | TDP1 (0.73) | TDP1MAPK1MAPTPOLBPKM | |
| SCHEMBL11542388 | 0.71 | TDP1 (0.73) | TDP1MAPK1MAPTPOLBPKM | |
| SCHEMBL4346024 | 0.71 | TDP1 (0.73) | TDP1MAPK1MAPTPOLBPKM | |
| SCHEMBL8192212 | 0.70 | HPGD (0.52) | TDP1MAPTCTDSP1ALDH1A1NR1I2 | |
| SCHEMBL27267549 | 0.70 | TDP1 (0.75) | TDP1MAPK1MAPTPOLBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020099858-A1 | CEPHALOSPORIN CIPROFLOXACIN HYBRID COMPOUNDS | IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY AND MEDICINE (GB) | 2020-05-22 | — | — | WO | disclosed |