Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | TOP2A | P11388 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.31 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.31 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.31 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22015243 | 0.89 | TDP1 (0.48) | MAPTTDP1L3MBTL1POLBCA5A | |
| SCHEMBL22015084 | 0.78 | TDP1 (0.54) | MAPTTDP1L3MBTL1POLBNR1I2 | |
| SCHEMBL22015083 | 0.78 | TDP1 (0.54) | MAPTTDP1L3MBTL1POLBNR1I2 | |
| SCHEMBL22015414 | 0.73 | TOP2A (0.44) | MAPTTOP2AALDH1A1HPGDKDM4E | |
| SCHEMBL16329562 | 0.69 | TOP2A (0.55) | MAPTTOP2AALDH1A1GAAHPGD | |
| SCHEMBL21894264 | 0.69 | TOP2A (0.42) | MAPTTOP2AALDH1A1HPGDKDM4E | |
| SCHEMBL16202385 | 0.68 | NR1I2 (0.47) | MAPTTDP1L3MBTL1POLBCA5A | |
| SCHEMBL11697100 | 0.67 | CA5A (0.57) | MAPTTDP1L3MBTL1POLBCA5A | |
| SCHEMBL11504463 | 0.67 | CA5A (0.57) | MAPTTDP1L3MBTL1POLBCA5A | |
| SCHEMBL8775559 | 0.66 | TOP2A (0.35) | POLBTOP2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020099858-A1 | CEPHALOSPORIN CIPROFLOXACIN HYBRID COMPOUNDS | IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY AND MEDICINE (GB) | 2020-05-22 | — | — | WO | disclosed |