Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 2/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | YAP1 | P46937 | 1/20 | 0.34 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.34 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24209504 | 0.82 | MAPT (0.43) | ALDH1A1GAACRHBPCRHR2KMT2A | |
| SCHEMBL22014820 | 0.80 | ACACB (0.40) | MAPTSMN1; SMN2YAP1TEAD4TEAD2 | |
| SCHEMBL22015790 | 0.79 | ALDH1A1 (0.35) | ALDH1A1GAAKMT2AMEN1MAPT | |
| SCHEMBL24209170 | 0.79 | ALDH1A1 (0.35) | ALDH1A1GAAKMT2AMEN1MAPT | |
| SCHEMBL24209211 | 0.79 | ALDH1A1 (0.35) | ALDH1A1GAAKMT2AMEN1MAPT | |
| SCHEMBL24209495 | 0.79 | ALDH1A1 (0.35) | ALDH1A1GAAKMT2AMEN1MAPT | |
| SCHEMBL22014798 | 0.79 | MEN1 (0.33) | ALDH1A1GAAKMT2AMEN1MAPT | |
| SCHEMBL24209291 | 0.79 | MEN1 (0.33) | ALDH1A1GAAKMT2AMEN1MAPT | |
| SCHEMBL22015449 | 0.79 | MEN1 (0.33) | ALDH1A1GAAKMT2AMEN1MAPT | |
| SCHEMBL21963759 | 0.79 | MEN1 (0.33) | ALDH1A1GAAKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020099886-A1 | LOX INHIBITORS | THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) | 2020-05-22 | — | — | WO | disclosed |