Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 11/20 | 0.42 |
| ▸ | CA2 | P00918 | 11/20 | 0.42 |
| ▸ | CA12 | O43570 | 9/20 | 0.42 |
| ▸ | CA9 | Q16790 | 7/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1455954 | 0.85 | TDP1 (0.57) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL5209649 | 0.84 | TDP1 (0.51) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL22015366 | 0.83 | TDP1 (0.47) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL5594018 | 0.81 | CA2 (0.45) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL21963755 | 0.80 | MEN1 (0.49) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL24625 | 0.80 | TDP1 (0.58) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL5213233 | 0.79 | TDP1 (0.53) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL7352046 | 0.79 | TDP1 (0.58) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL11897828 | 0.79 | TDP1 (0.46) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL18970801 | 0.77 | TDP1 (0.51) | TDP1MEN1GAAKMT2AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020099886-A1 | LOX INHIBITORS | THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) | 2020-05-22 | — | — | WO | disclosed |