SCHEMBL22015375

SCHEMBL22015375

CC1(C)CC2CN(CCS(=O)(=O)CCN)C[C@H]1N(c1ccc(N3CCS(=O)(=O)CC3)cc1)C2

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
KDM4E B2RXH2 1/20 0.31
RORC P51449 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24208967 1.00 ALDH1A1 (0.31) ALDH1A1KDM4ERORC
SCHEMBL24209224 1.00 ALDH1A1 (0.31) ALDH1A1KDM4ERORC
SCHEMBL22015103 1.00 ALDH1A1 (0.31) ALDH1A1KDM4ERORC
SCHEMBL24208996 0.84 ALDH1A1 (0.33) ALDH1A1KDM4E
SCHEMBL22015438 0.81 TP53 (0.33) ALDH1A1
SCHEMBL22014794 0.81 TP53 (0.33) ALDH1A1
SCHEMBL24209047 0.81 TP53 (0.33) ALDH1A1
SCHEMBL20898342 0.80 ALDH1A1 (0.32) ALDH1A1KDM4ERORC
SCHEMBL20907500 0.80 ALDH1A1 (0.32) ALDH1A1KDM4ERORC
Hydrochloric Acid SCHEMBL22555786 0.79 ALDH1A1 (0.31) ALDH1A1KDM4ERORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020099886-A1 LOX INHIBITORS THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) 2020-05-22 WO disclosed