Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | QPCT | Q16769 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | HTR1B | P28222 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28541808 | 0.75 | MAPT (0.40) | CYP1A2 | |
| SCHEMBL21241321 | 0.71 | CYP2E1 (0.49) | CYP1A2CYP2C9MAOAMAOB | |
| SCHEMBL9594869 | 0.68 | KMT2A (0.41) | — | |
| SCHEMBL22952501 | 0.68 | — | — | |
| SCHEMBL7863204 | 0.67 | CHKA (0.43) | — | |
| SCHEMBL28170375 | 0.67 | — | — | |
| SCHEMBL16040168 | 0.67 | NPC1 (0.58) | CYP1A2MAOAMAOB | |
| SCHEMBL25589622 | 0.66 | NOTUM (0.50) | CYP1A2CYP2C9MAOA | |
| SCHEMBL4869797 | 0.65 | ALDH1A1 (0.43) | CYP1A2 | |
| SCHEMBL4138501 | 0.62 | ALDH1A1 (0.31) | CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3218372-B1 | MORPHOLINE AND 1,4-OXAZEPANE AMIDES AS SOMATOSTATIN RECEPTOR SUBTYPE 4 (SSTR4) AGONISTS | BOEHRINGER INGELHEIM INT (DE) | 2020-05-20 | — | — | EP | disclosed |