SCHEMBL22015960

SCHEMBL22015960

Cc1cccn2c(C(C)(C)N[C@@H]3CNCCO3)nc(C3CC3)c12

nearest known ligand 0.69

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SSTR4 P31391 20/20 0.69
SSTR1 P30872 2/20 0.58
SSTR3 P32745 2/20 0.58
SSTR2 P30874 1/20 0.42
SSTR5 P35346 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22015762 0.85 SSTR4 (0.63) SSTR4SSTR1SSTR3SSTR2SSTR5
SCHEMBL17763046 0.82 SSTR4 (1.00) SSTR4SSTR1SSTR3SSTR2SSTR5
SCHEMBL17763066 0.77 SSTR4 (1.00) SSTR4SSTR1SSTR3
SCHEMBL22015657 0.74 SSTR4 (0.60) SSTR4SSTR1SSTR3
SCHEMBL19724490 0.73 SSTR4 (1.00) SSTR4SSTR1SSTR3
SCHEMBL16252717 0.73 SSTR4 (1.00) SSTR4SSTR1SSTR3
SCHEMBL17755102 0.73 SSTR4 (0.55) SSTR4SSTR1SSTR3
SCHEMBL17754948 0.72 SSTR4 (1.00) SSTR4SSTR1SSTR3SSTR2SSTR5
SCHEMBL17763074 0.72 SSTR4 (1.00) SSTR4SSTR1SSTR3SSTR2SSTR5
SCHEMBL17754913 0.71 SSTR4 (1.00) SSTR4SSTR1SSTR3SSTR2SSTR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3218372-B1 MORPHOLINE AND 1,4-OXAZEPANE AMIDES AS SOMATOSTATIN RECEPTOR SUBTYPE 4 (SSTR4) AGONISTS BOEHRINGER INGELHEIM INT (DE) 2020-05-20 EP disclosed