Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20470972 | 0.89 | MGLL (0.53) | MGLLSMN1; SMN2HPGDHTTPTGS1 | |
| SCHEMBL16172443 | 0.86 | MGLL (0.52) | MGLLSMN1; SMN2HPGDHTTPTGS1 | |
| SCHEMBL20830100 | 0.86 | MGLL (0.53) | MGLLSMN1; SMN2HPGDHTTPTGS1 | |
| SCHEMBL12532528 | 0.85 | MGLL (0.40) | MGLLSMN1; SMN2HPGDHTTPTGS1 | |
| SCHEMBL24621693 | 0.85 | MGLL (0.55) | MGLLSMN1; SMN2HPGDHTTPTGS1 | |
| SCHEMBL30259429 | 0.85 | MGLL (0.55) | MGLLSMN1; SMN2HPGDHTTPTGS1 | |
| SCHEMBL10018583 | 0.85 | MGLL (0.55) | MGLLSMN1; SMN2HPGDHTTPTGS1 | |
| SCHEMBL29441383 | 0.85 | MGLL (0.55) | MGLLSMN1; SMN2HPGDHTTPTGS1 | |
| SCHEMBL29869032 | 0.85 | MGLL (0.55) | MGLLSMN1; SMN2HPGDHTTPTGS1 | |
| SCHEMBL29608026 | 0.85 | MGLL (0.55) | MGLLSMN1; SMN2HPGDHTTPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11529422-B2 | Polymer linkers and their uses | NOVACYTE THERAPEUTICS COMPANY., LTD (CN) | 2022-12-20 | — | — | US | disclosed |
| US-20200155693-A1 | POLYMER LINKERS AND THEIR USES | NOVACYTE, INC. (US) | 2020-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11529422-B2 | Polymer linkers and their uses | PHF2, PHF8, PAICS | MGLL 4088/4885SMN1; SMN2 882/4885HPGD 802/4885 |
| US-20200155693-A1 | POLYMER LINKERS AND THEIR USES | PHF2, PHF8, PAICS | MGLL 4088/4885SMN1; SMN2 882/4885HPGD 802/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.