Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.37 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PLG | P00747 | 1/20 | 0.32 |
| ▸ | PLAT | P00750 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12435470 | 0.80 | MEN1 (0.40) | MEN1KMT2AHSD11B1L3MBTL1DUSP3 | |
| SCHEMBL1973469 | 0.76 | MEN1 (0.38) | MEN1KMT2AHSD11B1L3MBTL1DUSP3 | |
| SCHEMBL1973468 | 0.76 | MEN1 (0.38) | MEN1KMT2AHSD11B1L3MBTL1DUSP3 | |
| SCHEMBL31399939 | 0.76 | TSHR (0.46) | MEN1KMT2AL3MBTL1ALDH1A1LMNA | |
| SCHEMBL12436080 | 0.67 | MEN1 (0.38) | MEN1KMT2AHSD11B1L3MBTL1HCAR3 | |
| SCHEMBL11587975 | 0.65 | LMNA (0.39) | MEN1KMT2AL3MBTL1DUSP3LMNA | |
| SCHEMBL2586040 | 0.63 | PDE7A (0.41) | MEN1KMT2AHSD11B1L3MBTL1DUSP3 | |
| SCHEMBL31076314 | 0.63 | NPC1 (0.36) | MEN1KMT2ADUSP3ALDH1A1LMNA | |
| Cyclopropane Carboxylic Acid SCHEMBL10800712 | 0.63 | — | — | |
| SCHEMBL36093 | 0.63 | TSHR (0.61) | MEN1KMT2ADUSP3ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020099652-A1 | COMPOUNDS THAT SELECTIVELY AND EFFECTIVELY INHIBIT HAKAI-MEDIATED UBIQUITINATION, AS ANTI-CANCER DRUGS | FUNDACIÓN PROFESOR NOVOA SANTOS (ES) | 2020-05-22 | — | — | WO | disclosed |