Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.70 |
| ▸ | TSHR | P16473 | 4/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | CRHBP | P24387 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24210125 | 0.88 | ALDH1A1 (0.71) | ALDH1A1TSHRLMNACRHBPRAB9A | |
| SCHEMBL24209750 | 0.88 | ALDH1A1 (0.71) | ALDH1A1TSHRLMNACRHBPRAB9A | |
| SCHEMBL22009384 | 0.86 | ALDH1A1 (0.69) | ALDH1A1TSHRLMNACRHBPRAB9A | |
| SCHEMBL25334790 | 0.85 | ALDH1A1 (0.67) | ALDH1A1TSHRCRHBPRAB9ACRHR2 | |
| SCHEMBL25937563 | 0.81 | ALDH1A1 (0.66) | ALDH1A1TSHRLMNACRHBPRAB9A | |
| SCHEMBL24209789 | 0.79 | ALDH1A1 (0.61) | ALDH1A1TSHRLMNAGAAHPGD | |
| SCHEMBL24209735 | 0.77 | ALDH1A1 (0.58) | ALDH1A1TSHRLMNAGAAHPGD | |
| SCHEMBL24209736 | 0.77 | ALDH1A1 (0.58) | ALDH1A1TSHRLMNARAB9AHPGD | |
| SCHEMBL24209738 | 0.77 | GAA (0.68) | ALDH1A1TSHRLMNAGAAHPGD | |
| SCHEMBL24209629 | 0.74 | ALDH1A1 (0.54) | ALDH1A1TSHRLMNAGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020099652-A1 | COMPOUNDS THAT SELECTIVELY AND EFFECTIVELY INHIBIT HAKAI-MEDIATED UBIQUITINATION, AS ANTI-CANCER DRUGS | FUNDACIÓN PROFESOR NOVOA SANTOS (ES) | 2020-05-22 | — | — | WO | disclosed |