Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.52 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.52 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.43 |
| ▸ | ACLY | P53396 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | ACACA | Q13085 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | CPT2 | P23786 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.32 |
| ▸ | ELANE | P08246 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25078774 | 0.92 | CYP4F2 (0.50) | CYP4F2CYP4A11MEN1KMT2AELANE | |
| SCHEMBL19510111 | 0.92 | CYP4F2 (0.50) | CYP4F2CYP4A11MEN1KMT2AELANE | |
| SCHEMBL21109970 | 0.92 | CYP4F2 (0.50) | CYP4F2CYP4A11MEN1KMT2AELANE | |
| SCHEMBL23971207 | 0.90 | CYP4F2 (0.44) | CYP4F2CYP4A11DGAT1ACLYACACB | |
| SCHEMBL23970490 | 0.90 | CYP4F2 (0.44) | CYP4F2CYP4A11DGAT1ACLYACACB | |
| SCHEMBL17756699 | 0.89 | CYP4F2 (0.47) | CYP4F2CYP4A11DGAT1MEN1KMT2A | |
| SCHEMBL17746739 | 0.89 | CYP4F2 (0.61) | CYP4F2CYP4A11DGAT1ACLYACACB | |
| SCHEMBL31108876 | 0.88 | ACLY (0.61) | CYP4F2CYP4A11DGAT1ACLYTDP1 | |
| SCHEMBL1721309 | 0.87 | CYP4F2 (0.42) | CYP4F2CYP4A11DGAT1ACLYACACB | |
| SCHEMBL10975657 | 0.87 | CYP4F2 (0.42) | CYP4F2CYP4A11DGAT1ACLYACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3653598-A1 | PROCESSES AND INTERMEDIATES FOR PREPARING , -DICARBOXYLIC ACID-TERMINATED DIALKANE ETHERS | Gemphire Therapeutics Inc. (US) | 2020-05-20 | — | — | EP | disclosed |