⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24276408 | 0.92 | CYP2D6 (0.33) | — | |
| SCHEMBL22752283 | 0.87 | TSHR (0.41) | — | |
| SCHEMBL19978300 | 0.85 | HSD11B1 (0.33) | — | |
| SCHEMBL24330286 | 0.83 | GRIN2D (0.32) | — | |
| SCHEMBL24854974 | 0.83 | GRIN2D (0.35) | — | |
| SCHEMBL19251362 | 0.83 | TSHR (0.30) | — | |
| SCHEMBL27256684 | 0.83 | — | — | |
| SCHEMBL19251247 | 0.83 | — | — | |
| SCHEMBL23336397 | 0.81 | — | — | |
| SCHEMBL22752391 | 0.80 | TSHR (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230041518-A1 | QUINOLINE DERIVATIVES | GILEAD SCIENCES, INC. | 2023-02-09 | — | — | US | disclosed |
| US-11116760-B2 | Quinoline derivatives | GILEAD SCIENCES, INC. (US) | 2021-09-14 | — | — | US | disclosed |
| US-20200155538-A1 | QUINOLINE DERIVATIVES | GILEAD SCIENCES, INC. | 2020-05-21 | — | — | US | disclosed |