SCHEMBL2201700

SCHEMBL2201700

CC(C)c1ccc(-c2ccccc2OP(=O)(O)O)c(C(C)C)c1C(C)C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
INPPL1 O15357 6/20 0.40
INPP5A Q14642 4/20 0.40
INPP5B P32019 2/20 0.40
SRC P12931 3/20 0.40
KDM4E B2RXH2 1/20 0.40
USP2 O75604 1/20 0.40
ALDH1A1 P00352 1/20 0.40
HPGD P15428 1/20 0.40
PDE3A Q14432 1/20 0.40
HSD17B10 Q99714 1/20 0.40
AKT1 P31749 1/20 0.35
LMNA P02545 1/20 0.34
KMT2A Q03164 1/20 0.34
HTR2A P28223 1/20 0.34
S1PR1 P21453 1/20 0.33
PTPN5 P54829 1/20 0.32
ANPEP P15144 1/20 0.32
LAP3 P28838 1/20 0.32
NPC1 O15118 1/20 0.32
AKR1C3 P42330 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6246385 0.83 INPPL1 (0.46) INPPL1INPP5AINPP5BSRCKDM4E
SCHEMBL29597412 0.80 INPPL1 (0.47) INPPL1INPP5AINPP5BSRCKDM4E
SCHEMBL263927 0.80 INPPL1 (0.47) INPPL1INPP5AINPP5BSRCKDM4E
SCHEMBL31116689 0.79 INPPL1 (0.52) INPPL1INPP5AINPP5BSRCKDM4E
SCHEMBL1496214 0.79 INPPL1 (0.52) INPPL1INPP5AINPP5BSRCKDM4E
Ammonia Solution, Strong SCHEMBL28085268 0.79 INPPL1 (0.46) INPPL1INPP5AINPP5BSRCKDM4E
SCHEMBL28564162 0.78 PTPN5 (0.34) KDM4EALDH1A1LMNAKMT2APTPN5
SCHEMBL9645945 0.78 INPPL1 (0.61) INPPL1INPP5AINPP5BSRCKDM4E
SCHEMBL29259093 0.77 LMNA (0.32) LMNAKMT2AAKR1C3AKR1C2
Phosphoric Acid SCHEMBL29184304 0.77 PTPN5 (0.39) HPGDLMNAKMT2AS1PR1PTPN5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6579911-B1 Closed-cell polystyrene; less than 2.5% hexabromocyclododecane; a phosphorus compound, preferably triphenyl phosphate THE DOW CHEMICAL COMPANY 2003-06-17 US claimed
JP-2002523586-A 2002-07-30 JP claimed
EP-1112308-A1 FIRE RESISTANT STYRENE POLYMER FOAMS WITH REDUCED BROMINATED FIRE RETARDANT THE DOW CHEMICAL COMPANY (US) 2001-07-04 EP claimed
WO-2000012593-A1 FIRE RESISTANT STYRENE POLYMER FOAMS WITH REDUCED BROMINATED FIRE RETARDANT THE DOW CHEMICAL COMPANY (US) 2000-03-09 WO claimed
US-20220213250-A1 STORAGE STABLE HFO- OR HCFO-CONTAINING POLYOL COMPOSITIONS FOR MAKING FLAME-RESISTANT RIGID POLYURETHANE FOAMS DOW ITALIA S.R.L. (IT) 2022-07-07 US disclosed
EP-3976681-A1 STORAGE STABLE HFO- OR HCFO-CONTAINING POLYOL COMPOSITIONS FOR MAKING FLAME-RESISTANT RIGID POLYURETHANE FOAMS Dow Global Technologies LLC (US) 2022-04-06 EP disclosed
WO-2020242692-A1 STORAGE STABLE HFO- OR HCFO-CONTAINING POLYOL COMPOSITIONS FOR MAKING FLAME-RESISTANT RIGID POLYURETHANE FOAMS DOW GLOBAL TECHNOLOGIES LLC (US) 2020-12-03 WO disclosed
EP-1812726-B1 IMPACT-ABSORBING MEMBERS FOR DYNAMIC IMPACT APPLICATIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2015-08-26 EP disclosed
US-7977396-B2 Impact-absorbing members for dynamic impact applications DOW GLOBAL TECHNOLOGIES LLC (US) 2011-07-12 US disclosed
US-20060148919-A1 Impact-absorbing members for dynamic impact applications DOW GLOBAL TECHNOLOGIES LLC 2006-07-06 US disclosed