Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGFR | P43088 | 1/20 | 0.81 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 2/20 | 0.34 |
| ▸ | DPP4 | P27487 | 4/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ebopiprant SCHEMBL26496347 | 0.90 | PTGFR (1.00) | PTGFRLMNAALDH1A1MAPT | |
| Ebopiprant SCHEMBL26667891 | 0.90 | PTGFR (1.00) | PTGFRLMNAALDH1A1MAPT | |
| Ebopiprant SCHEMBL18055682 | 0.90 | PTGFR (1.00) | PTGFRLMNAALDH1A1MAPT | |
| Ebopiprant SCHEMBL19077960 | 0.90 | PTGFR (1.00) | PTGFRLMNAALDH1A1MAPT | |
| Ebopiprant SCHEMBL21142449 | 0.90 | PTGFR (1.00) | PTGFRLMNAALDH1A1MAPT | |
| Ebopiprant SCHEMBL24797015 | 0.90 | PTGFR (1.00) | PTGFRLMNAALDH1A1MAPT | |
| Ebopiprant SCHEMBL18055678 | 0.90 | PTGFR (1.00) | PTGFRLMNAALDH1A1MAPT | |
| Ebopiprant SCHEMBL18055681 | 0.89 | PTGFR (0.98) | PTGFRLMNAALDH1A1MAPT | |
| Ebopiprant SCHEMBL18055684 | 0.89 | PTGFR (0.98) | PTGFRLMNAALDH1A1MAPT | |
| Ebopiprant SCHEMBL26667889 | 0.89 | PTGFR (0.98) | PTGFRLMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11524003-B2 | Alpha-amino esters of hydroxypropylthiazolidine carboxamide derivative and salt form, crystal polymorph thereof | ObsEva S.A. (CH) | 2022-12-13 | — | — | US | disclosed |
| US-20200155515-A1 | ALPHA-AMINO ESTERS OF HYDROXYPROPYLTHIAZOLIDINE CARBOXAMIDE DERIVATIVE AND SALT FORM, CRYSTAL POLYMORPH THEREOF | XOMA (US) LLC | 2020-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200155515-A1 | ALPHA-AMINO ESTERS OF HYDROXYPROPYLTHIAZOLIDINE CARBOXAMIDE DERIVATIVE AND SALT FORM, CRYSTAL POLYMORPH THEREOF | PGF, PTGER1, PTGER4 | PTGFR 6/4885FKBP1A 973/4885MEN1 4822/4885 |
| US-11524003-B2 | Alpha-amino esters of hydroxypropylthiazolidine carboxamide derivative and salt form, crystal polymorph thereof | PGF, PTGER1, PTGER4 | PTGFR 6/4885FKBP1A 973/4885MEN1 4822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.