Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16993762 | 0.87 | MAPT (0.53) | LMNAALDH1A1ALOX12NPSR1GAA | |
| SCHEMBL16993761 | 0.87 | MAPT (0.53) | LMNAALDH1A1ALOX12NPSR1GAA | |
| Hydrochloric Acid SCHEMBL5702996 | 0.86 | MAPT (0.52) | LMNAALDH1A1ALOX12NPSR1GAA | |
| SCHEMBL22017070 | 0.86 | NPC1 (0.52) | LMNAALDH1A1GAAMAPTMEN1 | |
| Hydrochloric Acid SCHEMBL5703001 | 0.86 | MAPT (0.52) | LMNAALDH1A1ALOX12NPSR1GAA | |
| SCHEMBL31105648 | 0.84 | HTT (0.46) | LMNAALDH1A1ALOX12GAAMAPT | |
| SCHEMBL17395926 | 0.84 | HTT (0.46) | LMNAALDH1A1ALOX12GAAMAPT | |
| SCHEMBL17395927 | 0.84 | HTT (0.46) | LMNAALDH1A1ALOX12GAAMAPT | |
| SCHEMBL18137719 | 0.81 | GAA (0.43) | LMNAALDH1A1ALOX12NPSR1GAA | |
| SCHEMBL19449860 | 0.81 | MAPT (0.49) | LMNAALDH1A1ALOX12GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3164123-B1 | NOVEL THERAPEUTIC USES OF BENZYLIDENEGUANIDINE DERIVATIVES FOR THE TREATMENT OF PROTEOPATHIES | INFLECTIS BIOSCIENCE (FR) | 2020-05-20 | — | — | EP | disclosed |