Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24145636 | 0.89 | MAPK1 (0.34) | MAPK1CA1CA2CYP1A2CYP2C9 | |
| SCHEMBL22018316 | 0.83 | MAPK1 (0.38) | MAPK1CA1CA2CYP1A2CYP2C9 | |
| SCHEMBL22018099 | 0.81 | MAPK1 (0.35) | MAPK1CYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL22018304 | 0.80 | GABRA5 (0.39) | MAPK1CYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL22017885 | 0.80 | CA1 (0.38) | MAPK1CA1CA2CYP1A2CYP2C9 | |
| SCHEMBL22018315 | 0.79 | MEN1 (0.34) | MAPK1CA1CA2CYP1A2CYP2C9 | |
| SCHEMBL24145392 | 0.79 | CA1 (0.37) | MAPK1CA1CA2CYP1A2CYP2C9 | |
| SCHEMBL22018688 | 0.79 | MAPK1 (0.37) | MAPK1CA1CA2CYP1A2CYP2C9 | |
| SCHEMBL22018692 | 0.79 | MAPK1 (0.37) | MAPK1CA1CA2CYP1A2CYP2C9 | |
| SCHEMBL22018297 | 0.79 | BAZ2B (0.39) | CA2KDM4EHPGDPOLBHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210403435-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2021-12-30 | — | — | US | disclosed |
| WO-2020099367-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2020-05-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210403435-A1 | HERBICIDAL COMPOUNDS | DDT, CYP4X1, CYP1B1 | MAPK1 2679/4885CA1 1041/4885CA2 605/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.