Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | USP5 | P45974 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.30 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22018658 | 0.88 | GABRA5 (0.35) | KDM4EPOLBUSP5 | |
| SCHEMBL22018305 | 0.83 | HPGD (0.34) | HPGDMCOLN3KDM4EALDH1A1LMNA | |
| SCHEMBL22017867 | 0.80 | KDM4E (0.32) | KDM4EPOLB | |
| SCHEMBL22336368 | 0.79 | P4HTM (0.36) | HPGDKDM4EALDH1A1MAPTPOLB | |
| SCHEMBL22018295 | 0.79 | KDM4E (0.47) | KDM4EPOLBTSHR | |
| Hydrochloric Acid SCHEMBL22322580 | 0.78 | HCAR2 (0.39) | HPGDKDM4EALDH1A1MAPTPOLB | |
| Bromide SCHEMBL28625205 | 0.78 | KDM4E (0.46) | KDM4EPOLBTSHR | |
| Bromide SCHEMBL28625208 | 0.78 | KDM4E (0.46) | KDM4EPOLBTSHR | |
| SCHEMBL22017881 | 0.77 | BRD4 (0.33) | — | |
| SCHEMBL22322578 | 0.77 | KDM4E (0.33) | KDM4EPOLBTSHRCYP2D6HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020099367-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2020-05-22 | — | — | WO | disclosed |