Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.46 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.46 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.46 |
| ▸ | PLK1 | P53350 | 6/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | HPGDS | O60760 | 2/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.41 |
| ▸ | STAMBP | O95630 | 1/20 | 0.41 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25060913 | 0.81 | HCAR2 (0.59) | HCAR2HDAC8HDAC6HDAC2 | |
| SCHEMBL21408728 | 0.81 | RAB9A (0.54) | HCAR2HPGDSMN1; SMN2 | |
| SCHEMBL21408725 | 0.79 | HCAR2 (0.44) | HCAR2MKNK1MKNK2BAZ2BPLK1 | |
| SCHEMBL1880894 | 0.79 | KDM4E (0.61) | HCAR2HTTCA2 | |
| SCHEMBL21431896 | 0.79 | TP53 (0.65) | HCAR2HPGDHTTSMN1; SMN2 | |
| SCHEMBL6415026 | 0.79 | HCAR2 (0.52) | HCAR2HPGDHTTSMN1; SMN2HPGDS | |
| SCHEMBL20753429 | 0.78 | BAZ2B (0.46) | HCAR2HDAC8HDAC6HDAC2MKNK1 | |
| SCHEMBL22336227 | 0.77 | P4HTM (0.55) | HCAR2 | |
| SCHEMBL13113096 | 0.76 | HCAR2 (0.48) | HCAR2HTTSMN1; SMN2 | |
| SCHEMBL2896973 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114080155-B | Shear stable composition for spray drift control | 巴斯夫欧洲公司 | 2024-03-26 | — | — | CN | disclosed |
| WO-2023220131-A2 | PI3Kα INHIBITORS AND METHODS OF USE THEREOF | RELAY THERAPEUTICS, INC. (US) | 2023-11-16 | — | — | WO | disclosed |
| US-20210403435-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2021-12-30 | — | — | US | disclosed |
| US-20210403435-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2021-12-30 | — | — | US | disclosed |
| CN-113329629-A | Herbicidal compounds | 先正达农作物保护股份公司 | 2021-08-31 | — | — | CN | disclosed |
| WO-2020099367-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2020-05-22 | — | — | WO | disclosed |
| CN-105793256-B | Imdazole derivatives | 豪夫迈·罗氏有限公司 | 2019-09-10 | — | — | CN | disclosed |
| CN-109561680-A | small molecule modulators of pantothenate kinase | 圣朱德儿童研究医院 | 2019-04-02 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210403435-A1 | HERBICIDAL COMPOUNDS | DDT, CYP4X1, CYP1B1 | HCAR2 1075/4885HDAC8 1486/4885HDAC6 650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.