Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 16/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 16/20 | 0.43 |
| ▸ | BPTF | Q12830 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29117985 | 0.89 | HCRTR1 (0.51) | HCRTR1HCRTR2 | |
| SCHEMBL21963537 | 0.89 | HCRTR1 (0.51) | HCRTR1HCRTR2 | |
| SCHEMBL1670922 | 0.89 | HCRTR1 (0.51) | HCRTR1HCRTR2 | |
| Hydrochloric Acid SCHEMBL29367258 | 0.87 | HCRTR1 (0.50) | HCRTR1HCRTR2 | |
| Hydrochloric Acid SCHEMBL15796256 | 0.87 | HCRTR1 (0.50) | HCRTR1HCRTR2 | |
| SCHEMBL6923122 | 0.81 | HCRTR1 (0.44) | HCRTR1HCRTR2 | |
| SCHEMBL29118005 | 0.78 | ROCK2 (0.50) | HCRTR1HCRTR2 | |
| SCHEMBL29118006 | 0.78 | ROCK2 (0.50) | HCRTR1HCRTR2 | |
| SCHEMBL29118052 | 0.78 | ROCK2 (0.50) | HCRTR1HCRTR2 | |
| SCHEMBL29614755 | 0.78 | HCRTR1 (0.43) | HCRTR1HCRTR2BPTF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020100011-A1 | IMPROVED SYNTHETIC METHODS OF MAKING FUSED HETEROCYCLIC COMPOUNDS AS OREXIN RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-05-22 | — | — | WO | disclosed |