⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18085982 | 0.69 | — | — | |
| SCHEMBL12741070 | 0.64 | SOS1 (0.31) | — | |
| SCHEMBL9910016 | 0.63 | — | — | |
| SCHEMBL12065981 | 0.62 | — | — | |
| SCHEMBL14030432 | 0.60 | — | — | |
| SCHEMBL21690259 | 0.60 | — | — | |
| SCHEMBL12727657 | 0.59 | — | — | |
| SCHEMBL24736595 | 0.58 | — | — | |
| SCHEMBL12741065 | 0.58 | — | — | |
| SCHEMBL24849291 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10660968-B2 | Spirocyclic degronimers for target protein degradation | C4 THERAPEUTICS, INC. (US) | 2020-05-26 | — | — | US | disclosed |