Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21932888 | 0.76 | IKZF2 (0.33) | — | |
| SCHEMBL21932896 | 0.65 | IKZF2 (0.42) | — | |
| SCHEMBL21932889 | 0.60 | — | — | |
| SCHEMBL21963500 | 0.60 | CRBN (0.38) | TP53 | |
| SCHEMBL22018808 | 0.60 | CRBN (0.40) | — | |
| SCHEMBL21932917 | 0.60 | CRBN (0.52) | — | |
| SCHEMBL22000761 | 0.59 | CRBN (0.51) | — | |
| SCHEMBL22000914 | 0.59 | CRBN (0.51) | — | |
| SCHEMBL21349280 | 0.55 | GRM2 (0.41) | — | |
| SCHEMBL30270636 | 0.55 | CRBN (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102195-A1 | SUBSTITUTED ISOINDOLINONES | BIOTHERYX, INC. (US) | 2020-05-22 | — | — | WO | disclosed |