Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.54 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26124000 | 0.90 | BACE1 (0.61) | BACE1GRIN1GRIN2AHTR2AOPRM1 | |
| SCHEMBL5004601 | 0.77 | BACE1 (0.82) | BACE1HTR2AOPRM1OPRK1OPRL1 | |
| SCHEMBL22018461 | 0.77 | BACE1 (0.54) | BACE1HTR2AOPRM1OPRK1OPRL1 | |
| SCHEMBL31596433 | 0.77 | BACE1 (0.82) | BACE1HTR2AOPRM1OPRK1OPRL1 | |
| Hydrochloric Acid SCHEMBL6639413 | 0.76 | BACE1 (0.79) | BACE1HTR2AOPRM1OPRK1OPRL1 | |
| SCHEMBL30548894 | 0.75 | BACE1 (0.46) | BACE1HTR2AOPRM1OPRK1OPRL1 | |
| SCHEMBL6636367 | 0.73 | BACE1 (0.79) | BACE1HTR2AOPRM1OPRK1OPRL1 | |
| SCHEMBL9726922 | 0.72 | GRIN1 (0.38) | GRIN1GRIN2AGRIN2B | |
| Hydrochloric Acid SCHEMBL6638886 | 0.72 | BACE1 (0.77) | BACE1HTR2AOPRM1OPRK1OPRL1 | |
| SCHEMBL29609089 | 0.72 | BACE1 (0.64) | BACE1HTR2AOPRM1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10660968-B2 | Spirocyclic degronimers for target protein degradation | C4 THERAPEUTICS, INC. (US) | 2020-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10660968-B2 | Spirocyclic degronimers for target protein degradation | STUB1, UBE3C, UBE3A | BACE1 1584/4885GRIN1 3819/4885GRIN2A 3881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.