Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PPM1B | O75688 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.34 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.34 |
| ▸ | GLB1 | P16278 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3316703 | 1.00 | DPP4 (0.37) | DPP4DPP8DPP9KDM4ECYP1A2 | |
| SCHEMBL1567974 | 1.00 | DPP4 (0.37) | DPP4DPP8DPP9KDM4ECYP1A2 | |
| SCHEMBL9684605 | 1.00 | DPP4 (0.37) | DPP4DPP8DPP9KDM4ECYP1A2 | |
| SCHEMBL4892915 | 1.00 | DPP4 (0.37) | DPP4DPP8DPP9KDM4ECYP1A2 | |
| SCHEMBL1470851 | 1.00 | DPP4 (0.37) | DPP4DPP8DPP9KDM4ECYP1A2 | |
| SCHEMBL2389792 | 1.00 | DPP4 (0.37) | DPP4DPP8DPP9KDM4ECYP1A2 | |
| Hydrochloric Acid SCHEMBL7312757 | 0.98 | KDM4E (0.38) | DPP4DPP8DPP9KDM4ECYP1A2 | |
| Hydrochloric Acid SCHEMBL2705454 | 0.98 | KDM4E (0.38) | DPP4DPP8DPP9KDM4ECYP1A2 | |
| Hydrochloric Acid SCHEMBL132277 | 0.98 | KDM4E (0.38) | DPP4DPP8DPP9KDM4ECYP1A2 | |
| Hydrochloric Acid SCHEMBL7306465 | 0.98 | KDM4E (0.38) | DPP4DPP8DPP9KDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912994-B1 | ADENINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2014-03-12 | — | — | EP | disclosed |
| US-7977343-B2 | Adenine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-07-12 | — | — | US | disclosed |
| US-20100160352-A1 | ADENINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2010-06-24 | — | — | US | disclosed |
| EP-1912994-A1 | ADENINE DERIVATIVES | Merck Patent GmbH (DE) | 2008-04-23 | — | — | EP | disclosed |
| CN-100351231-C | Lipid metabolism-improving agent | KYOWA HAKKO KOGYO KK (JP) | 2007-11-28 | — | — | CN | disclosed |
| WO-2007017069-A1 | ADENINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2007-02-15 | — | — | WO | disclosed |
| CN-1777581-A | Therapeutic agent for diabetes | KYOWA HAKKO KOGYO KK (JP) | 2006-05-24 | — | — | CN | disclosed |
| CN-1756741-A | Lipid metabolism-improving agent | KYOWA HAKKO KOGYO KK (JP) | 2006-04-05 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160352-A1 | ADENINE DERIVATIVES | HSP90AA1, TRAP1, HSP90AB1 | DPP4 4398/4885DPP8 4447/4885DPP9 4399/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.