Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | TYR | P14679 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | ADK | P55263 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20785196 | 0.78 | CA12 (0.45) | HTTIDO1TYRALDH1A1GAA | |
| SCHEMBL18627679 | 0.77 | IDO1 (0.43) | HTTIDO1TYRALDH1A1GAA | |
| SCHEMBL3099378 | 0.76 | MAOA (0.41) | IDO1CA1CA2 | |
| SCHEMBL7372396 | 0.75 | AOC3 (0.40) | HTTALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL5018098 | 0.75 | TYR (0.41) | HTTIDO1TYRALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL9879585 | 0.74 | MAOA (0.39) | IDO1 | |
| Bromide SCHEMBL31621147 | 0.74 | CYP2A6 (0.36) | HTTALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL12922764 | 0.74 | TYR (0.44) | HTTIDO1TYRALDH1A1KDM4E | |
| SCHEMBL18805967 | 0.74 | TYR (0.44) | HTTIDO1TYRALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL6287950 | 0.73 | AOC3 (0.39) | HTTALDH1A1KDM4ELMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3653054-A1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | Vanderbilt University (US) | 2020-05-20 | — | — | EP | disclosed |