Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 8/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22017895 | 0.86 | SMN1; SMN2 (0.42) | SMN1; SMN2HPGDALDH1A1LMNAPKM | |
| SCHEMBL22018290 | 0.84 | CA12 (0.41) | HPGDALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL22018302 | 0.83 | SMN1; SMN2 (0.40) | SMN1; SMN2HPGDALDH1A1LMNAPKM | |
| SCHEMBL22018040 | 0.82 | KDM4E (0.48) | SMN1; SMN2HPGDALDH1A1MEN1KMT2A | |
| SCHEMBL22018672 | 0.81 | SMN1; SMN2 (0.47) | SMN1; SMN2HPGDALDH1A1LMNAPKM | |
| SCHEMBL28634617 | 0.81 | CA2 (0.41) | SMN1; SMN2HPGDHTT | |
| SCHEMBL22018666 | 0.81 | CA2 (0.50) | KMT2AKDM4E | |
| SCHEMBL22018656 | 0.81 | KMT2A (0.42) | SMN1; SMN2HPGDALDH1A1LMNAMEN1 | |
| SCHEMBL22018041 | 0.80 | CA2 (0.44) | CYP2C9 | |
| SCHEMBL22018668 | 0.80 | CA2 (0.50) | ALDH1A1LMNAKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020099367-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2020-05-22 | — | — | WO | disclosed |