Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22018558 | 0.84 | ALDH1A1 (0.49) | ALDH1A1HPGDPOLBTSHRMAPT | |
| SCHEMBL22018763 | 0.82 | MAPK1 (0.38) | ALDH1A1HPGDTP53POLBMAPK1 | |
| SCHEMBL13831399 | 0.81 | POLB (0.59) | ALDH1A1HPGDPOLBMAPK1KMT2A | |
| SCHEMBL22019637 | 0.80 | KDM4E (0.30) | ALDH1A1HPGD | |
| SCHEMBL22018917 | 0.78 | ALDH1A1 (0.36) | ALDH1A1HPGDTP53KMT2AMEN1 | |
| SCHEMBL13832337 | 0.78 | POLB (0.59) | ALDH1A1HPGDPOLBMAPK1KMT2A | |
| SCHEMBL22019356 | 0.74 | ALDH1A1 (0.53) | ALDH1A1POLBKMT2AMEN1TSHR | |
| SCHEMBL22018565 | 0.73 | ALDH1A1 (0.47) | ALDH1A1HPGDPOLBMAPK1KMT2A | |
| SCHEMBL13832334 | 0.72 | ALDH1A1 (0.57) | ALDH1A1HPGDTP53POLBMAPK1 | |
| SCHEMBL13832305 | 0.68 | POLB (0.58) | ALDH1A1HPGDPOLBMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3653054-A1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | Vanderbilt University (US) | 2020-05-20 | — | — | EP | disclosed |