Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 4/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | RAF1 | P04049 | 1/20 | 0.42 |
| ▸ | BRAF | P15056 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | VNN1 | O95497 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.41 |
| ▸ | MLYCD | O95822 | 4/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22019150 | 0.94 | SCD (0.47) | SCDCYP2C9CYP2C19KDM4EALDH1A1 | |
| SCHEMBL21962769 | 0.94 | SCD (0.47) | SCDCYP2C9CYP2C19KDM4EALDH1A1 | |
| SCHEMBL21962751 | 0.92 | SCD (0.44) | SCDCYP2C9CYP2C19KDM4EALDH1A1 | |
| SCHEMBL22019127 | 0.86 | RAF1 (0.42) | SCDCYP2C9CYP2C19KDM4EALDH1A1 | |
| SCHEMBL21962431 | 0.86 | RAF1 (0.42) | SCDCYP2C9CYP2C19KDM4EALDH1A1 | |
| SCHEMBL21962446 | 0.86 | SCD (0.46) | SCDCYP2C9CYP2C19KDM4EALDH1A1 | |
| SCHEMBL21962542 | 0.85 | RAF1 (0.48) | SCDCYP2C9CYP2C19KDM4EALDH1A1 | |
| SCHEMBL21962674 | 0.84 | SCD (0.47) | SCDCYP2C9CYP2C19KDM4EALDH1A1 | |
| SCHEMBL21962458 | 0.83 | SCD (0.46) | SCDCYP2C9CYP2C19KDM4EALDH1A1 | |
| SCHEMBL22020545 | 0.83 | HDAC3 (0.44) | SCDCYP2C9CYP2C19KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102575-A1 | HETEROCYCLIC AMINOTHIAZOLES AND USES THEREOF | INCEPTION IBD, INC. (US) | 2020-05-22 | — | — | WO | disclosed |