Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 3/20 | 0.47 |
| ▸ | VNN1 | O95497 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RAF1 | P04049 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21962769 | 1.00 | SCD (0.47) | SCDVNN1KDM4EALDH1A1CYP2C9 | |
| SCHEMBL22019128 | 0.94 | SCD (0.52) | SCDVNN1KDM4EALDH1A1CYP2C9 | |
| SCHEMBL21962751 | 0.90 | SCD (0.44) | SCDVNN1KDM4EALDH1A1CYP2C9 | |
| SCHEMBL21962552 | 0.87 | IDH2 (0.48) | SCDVNN1KDM4EALDH1A1CYP2C9 | |
| SCHEMBL22019585 | 0.87 | VNN1 (0.44) | SCDVNN1KDM4EALDH1A1CYP2C9 | |
| SCHEMBL21962851 | 0.87 | VNN1 (0.44) | SCDVNN1KDM4EALDH1A1CYP2C9 | |
| SCHEMBL21962442 | 0.86 | MLYCD (0.39) | SCDVNN1LMNA | |
| SCHEMBL22020538 | 0.86 | MLYCD (0.39) | SCDVNN1LMNA | |
| SCHEMBL21962681 | 0.86 | VNN1 (0.44) | SCDVNN1KDM4EALDH1A1CYP2C9 | |
| SCHEMBL22019152 | 0.86 | VNN1 (0.44) | SCDVNN1KDM4EALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102575-A1 | HETEROCYCLIC AMINOTHIAZOLES AND USES THEREOF | INCEPTION IBD, INC. (US) | 2020-05-22 | — | — | WO | disclosed |