Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | FABP4 | P15090 | 1/20 | 0.30 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24978475 | 0.91 | NLRP3 (0.33) | NLRP3USP2 | |
| SCHEMBL22020382 | 0.88 | NLRP3 (0.46) | NLRP3USP2FABP4FABP5 | |
| SCHEMBL22021253 | 0.87 | NLRP3 (0.34) | NLRP3USP2FABP4FABP5 | |
| SCHEMBL24978235 | 0.83 | NLRP3 (0.47) | NLRP3USP2 | |
| SCHEMBL24978272 | 0.83 | NLRP3 (0.47) | NLRP3USP2 | |
| SCHEMBL24978023 | 0.82 | NLRP3 (0.37) | NLRP3USP2 | |
| SCHEMBL22021100 | 0.80 | USP2 (0.34) | NLRP3USP2 | |
| SCHEMBL23481702 | 0.77 | — | — | |
| SCHEMBL22021427 | 0.75 | NLRP3 (0.34) | NLRP3USP2 | |
| SCHEMBL22012175 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102096-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS INFLAMMASOME RESEARCH, INC. (US) | 2020-05-22 | — | — | WO | disclosed |