SCHEMBL22019925

SCHEMBL22019925

Clc1nc(-c2ccccc2)nc(-c2cccc3c2c2ccccc2n3-c2ccc(-c3ccccc3)cc2)n1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.43
POLB P06746 2/20 0.43
CTDSP1 Q9GZU7 1/20 0.43
NPSR1 Q6W5P4 1/20 0.38
RXFP1 Q9HBX9 1/20 0.38
ATM Q13315 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
HDAC4 P56524 1/20 0.36
MAPK14 Q16539 1/20 0.34
ABCG2 Q9UNQ0 2/20 0.33
PDE5A O76074 2/20 0.33
RORC P51449 1/20 0.33
PDE6D O43924 1/20 0.33
ADORA3 P0DMS8 1/20 0.33
ALOX15 P16050 1/20 0.33
TSHR P16473 1/20 0.33
ADORA2A P29274 1/20 0.33
ADORA2B P29275 1/20 0.33
ADORA1 P30542 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22087533 0.98 KDM4E (0.46) KDM4EPOLBCTDSP1NPSR1RXFP1
SCHEMBL20560777 0.95 KDM4E (0.48) KDM4EPOLBCTDSP1NPSR1RXFP1
SCHEMBL29768812 0.95 KDM4E (0.48) KDM4EPOLBCTDSP1NPSR1RXFP1
SCHEMBL21365537 0.94 ATM (0.42) KDM4EATML3MBTL1HDAC4PDE5A
SCHEMBL22386967 0.94 ATM (0.42) KDM4EATML3MBTL1HDAC4PDE5A
SCHEMBL24272982 0.94 ATM (0.42) KDM4EATML3MBTL1HDAC4PDE5A
SCHEMBL24152522 0.91 KDM4E (0.47) KDM4EPOLBCTDSP1ATML3MBTL1
SCHEMBL22024474 0.90 KDM4E (0.41) KDM4EPOLBCTDSP1ATML3MBTL1
SCHEMBL24272984 0.90 ATM (0.39) KDM4ERXFP1ATML3MBTL1HDAC4
SCHEMBL24272993 0.90 ATM (0.39) KDM4ERXFP1ATML3MBTL1HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220020932-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2022-01-20 US disclosed
WO-2020101169-A1 COMPOUND FOR ORGANIC ELECTRONIC DEVICE, ORGANIC ELECTRONIC DEVICE USING SAME, AND ELECTRONIC APPARATUS THEREOF 덕산네오룩스 주식회사 2020-05-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220020932-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF PIEZO1, OR51E2, OR10J3 KDM4E 636/4885POLB 2368/4885CTDSP1 3714/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.