Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | SAT1 | P21673 | 2/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24474442 | 0.91 | TSHR (0.50) | TSHRCYP2C19CYP1A2KDM1AALDH1A1 | |
| SCHEMBL28316696 | 0.89 | TSHR (0.52) | TSHRCYP2C19CYP1A2KDM1AALDH1A1 | |
| SCHEMBL19033247 | 0.88 | ALDH1A1 (0.48) | TSHRCYP2C19CYP1A2ALDH1A1CYP3A4 | |
| SCHEMBL22624698 | 0.88 | ALDH1A1 (0.43) | TSHRCYP2C19CYP1A2ALDH1A1CYP3A4 | |
| SCHEMBL14139579 | 0.85 | TSHR (0.54) | TSHRCYP2C19CYP1A2KDM1AALDH1A1 | |
| SCHEMBL18937359 | 0.83 | ALDH1A1 (0.48) | TSHRCYP2C19CYP1A2KDM1AALDH1A1 | |
| SCHEMBL25701264 | 0.83 | ALDH1A1 (0.48) | TSHRCYP2C19CYP1A2KDM1AALDH1A1 | |
| SCHEMBL22625620 | 0.83 | ALDH1A1 (0.58) | TSHRCYP2C19CYP1A2KDM1AALDH1A1 | |
| SCHEMBL12478812 | 0.83 | ALDH1A1 (0.59) | TSHRCYP2C19CYP1A2ALDH1A1CYP3A4 | |
| SCHEMBL24673319 | 0.82 | ALDH1A1 (0.53) | TSHRALDH1A1CYP3A4TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3653648-A1 | SUBSTRATE COVERED WITH POLYMERS FOR SELECTIVE SEPARATION OF CELLS OR FOR CELL CULTURING | National University Corporation University Of Toyama (JP) | 2020-05-20 | — | — | EP | disclosed |