Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.61 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | SCN1A | P35498 | 2/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | TYK2 | P29597 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22020136 | 0.91 | USP30 (0.62) | USP30RIOK2ALDH1A1GAAL3MBTL1 | |
| SCHEMBL4271035 | 0.89 | USP30 (0.60) | USP30RIOK2ALDH1A1GAAL3MBTL1 | |
| SCHEMBL16254222 | 0.79 | USP30 (0.64) | USP30RIOK2ALDH1A1GAAL3MBTL1 | |
| SCHEMBL22653435 | 0.76 | USP30 (1.00) | USP30 | |
| SCHEMBL29878272 | 0.76 | USP30 (1.00) | USP30 | |
| SCHEMBL16254943 | 0.74 | RIOK2 (0.60) | USP30RIOK2ALDH1A1GAAL3MBTL1 | |
| SCHEMBL12004497 | 0.74 | USP30 (0.58) | USP30RIOK2FFAR4EPHX2SYK | |
| SCHEMBL6862768 | 0.74 | USP30 (0.58) | USP30RIOK2FFAR4EPHX2SYK | |
| SCHEMBL12004494 | 0.74 | USP30 (0.58) | USP30RIOK2FFAR4EPHX2SYK | |
| SCHEMBL23060730 | 0.70 | RIOK2 (0.61) | USP30RIOK2ALDH1A1GAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3189839-B1 | N-PIPERIDINYL ACETAMIDE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | PRAXIS PREC MEDICINES INC (US) | 2020-05-20 | — | — | EP | disclosed |