Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.34 |
| ▸ | TACR2 | P21452 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2972599 | 1.00 | TYR (0.40) | TYRLIPGTP53CYP3A4MEN1 | |
| SCHEMBL2970338 | 1.00 | TYR (0.40) | TYRLIPGTP53CYP3A4MEN1 | |
| SCHEMBL2973974 | 1.00 | TYR (0.40) | TYRLIPGTP53CYP3A4MEN1 | |
| SCHEMBL2966081 | 1.00 | TYR (0.40) | TYRLIPGTP53CYP3A4MEN1 | |
| SCHEMBL2967957 | 1.00 | TYR (0.40) | TYRLIPGTP53CYP3A4MEN1 | |
| SCHEMBL2973976 | 1.00 | TYR (0.40) | TYRLIPGTP53CYP3A4MEN1 | |
| SCHEMBL815591 | 1.00 | TYR (0.40) | TYRLIPGTP53CYP3A4MEN1 | |
| SCHEMBL2972345 | 1.00 | TYR (0.40) | TYRLIPGTP53CYP3A4MEN1 | |
| SCHEMBL4593571 | 0.98 | TYR (0.41) | TYRLIPGTP53CYP3A4MEN1 | |
| SCHEMBL981990 | 0.98 | TYR (0.38) | TYRLIPGTP53CYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7977504-B2 | Process for producing isocyanates and aromatic hydroxy compounds | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2011-07-12 | — | — | US | disclosed |
| US-20100274047-A1 | PROCESS FOR PRODUCING OF ISOCYANATES AND AROMATIC HYDROXY COMPOUNDS | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2010-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100274047-A1 | PROCESS FOR PRODUCING OF ISOCYANATES AND AROMATIC HYDROXY COMPOUNDS | PAH, APEH, HPD | TYR 138/4885LIPG 2599/4885TP53 2384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.