⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28963573 | 0.73 | — | — | |
| SCHEMBL7844333 | 0.72 | — | — | |
| SCHEMBL27945 | 0.70 | — | — | |
| SCHEMBL3089980 | 0.68 | — | — | |
| SCHEMBL16097873 | 0.67 | — | — | |
| SCHEMBL381189 | 0.67 | — | — | |
| SCHEMBL43584 | 0.67 | — | — | |
| SCHEMBL1229133 | 0.67 | — | — | |
| SCHEMBL21828481 | 0.67 | — | — | |
| SCHEMBL43918 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10154995-B2 | Serine/threonine kinase inhibitors | ARRAY BIOPHARMA INC. (US) | 2018-12-18 | — | — | US | disclosed |
| EP-3089788-B1 | SERINE/THREONINE KINASE INHIBITORS | GENENTECH INC (US) | 2018-10-24 | — | — | EP | disclosed |
| EP-3089980-B1 | SERINE/THREONINE KINASE INHIBITORS | ARRAY BIOPHARMA INC (US) | 2018-01-31 | — | — | EP | disclosed |
| US-20170348310-A1 | SERINE/THREONINE KINASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2017-12-07 | — | — | US | disclosed |
| US-9763942-B2 | Serine/threonine kinase inhibitors | GENENTECH, INC. (US) | 2017-09-19 | — | — | US | disclosed |
| US-9670208-B2 | Serine/threonine kinase inhibitors | ARRAY BIOPHARMA INC. (US) | 2017-06-06 | — | — | US | disclosed |
| EP-3089980-A1 | SERINE/THREONINE KINASE INHIBITORS | Array Biopharma, Inc. (US) | 2016-11-09 | — | — | EP | disclosed |
| EP-3089788-A1 | SERINE/THREONINE KINASE INHIBITORS | Genentech, Inc. (US) | 2016-11-09 | — | — | EP | disclosed |
| US-20160303126-A1 | SERINE/THREONINE KINASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2016-10-20 | — | — | US | disclosed |
| US-20160304519-A1 | SERINE/THREONINE KINASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2016-10-20 | — | — | US | disclosed |
| US-7977670-B2 | Organic transistor | TOYO INK MFG. CO., LTD. (JP) | 2011-07-12 | — | — | US | disclosed |
| US-20100032657-A1 | ORGANIC TRANSISTOR | TOYO INK MFG CO., LTD (JP) | 2010-02-11 | — | — | US | disclosed |
| EP-2085379-A1 | Arylsulfonamido-substituted hydroxamic acid derivatives | Novartis AG (CH) | 2009-08-05 | — | — | EP | disclosed |
| US-20080275127-A1 | Arylsulfonamido-substituted hydroxamic acid derivatives | BREITENSTEIN WERNER | 2008-11-06 | — | — | US | disclosed |
| US-7138432-B1 | Arylsulfonamido-substituted hydroxamic acid derivatives | NOVARTIS AG (CH) | 2006-11-21 | — | — | US | disclosed |
| CN-1215055-C | Arylsulfonylamino-substituted hydroxamic acid derivatives | NOVARTIS AG (CH) | 2005-08-17 | — | — | CN | disclosed |
| CN-1368958-A | Arylsulfonamido-substituted hydroxamic acid derivatives | NOVARTIS AG (CH) | 2002-09-11 | — | — | CN | disclosed |
| EP-1202961-A1 | ARYLSULFONAMIDO-SUBSTITUTED HYDROXAMIC ACID DERIVATIVES | Novartis AG (CH) | 2002-05-08 | — | — | EP | disclosed |
| WO-2001010827-A1 | ARYLSULFONAMIDO-SUBSTITUTED HYDROXAMIC ACID DERIVATIVES | NOVARTIS AG (CH) | 2001-02-15 | — | — | WO | disclosed |
| WO-1999033790-A1 | INSECTICIDAL FLUORO-SUBSTITUTED BENZOYLUREAS | NIHON BAYER AGROCHEM K.K. (DE) | 1999-07-08 | — | — | WO | disclosed |