⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12039711 | 0.88 | — | — | |
| SCHEMBL15255663 | 0.87 | TSHR (0.31) | — | |
| SCHEMBL20755869 | 0.83 | — | — | |
| SCHEMBL443124 | 0.80 | OPRM1 (0.31) | — | |
| SCHEMBL15534431 | 0.79 | CYP2D6 (0.31) | — | |
| SCHEMBL24584371 | 0.78 | — | — | |
| SCHEMBL29140307 | 0.76 | — | — | |
| SCHEMBL26769494 | 0.76 | — | — | |
| SCHEMBL10141730 | 0.75 | CYP2D6 (0.31) | — | |
| SCHEMBL25518535 | 0.75 | CYP1A2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4289847-A1 | PIM KINASE INHIBITOR | Hangzhou Biosun Pharmaceutical Co., Ltd. (CN) | 2023-12-13 | — | — | EP | disclosed |
| US-11691989-B2 | Macrocyclic indoles as Mcl-1 inhibitors | ASCENTAGE PHARMA (SUZHOU) CO., LTD. (CN) | 2023-07-04 | — | — | US | disclosed |
| US-20220396587-A1 | MACROCYCLIC FUSED PYRRAZOLES AS MCL-1 INHIBITORS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2022-12-15 | — | — | US | disclosed |
| US-11168082-B2 | Pyrrolo[2,3-C]pyridines and related analogs as LSD-1 inhibitors | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2021-11-09 | — | — | US | disclosed |
| US-20200157091-A1 | PYRROLO[2,3-C]PYRIDINES AND RELATED ANALOGS AS LSD-1 INHIBITORS | UNIV MICHIGAN REGENTS (US) | 2020-05-21 | — | — | US | disclosed |