SCHEMBL2202080

SCHEMBL2202080

CC(c1ccccc1N)(c1ccccc1N)c1ccccc1N

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.47
ALOX15 P16050 2/20 0.47
CASP1 P29466 1/20 0.47
CASP7 P55210 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
TDP1 Q9NUW8 4/20 0.42
ALDH1A1 P00352 7/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
TSHR P16473 6/20 0.39
PIK3CA P42336 1/20 0.39
GAA P10253 3/20 0.39
ADRA2B P18089 1/20 0.39
PTGS1 P23219 1/20 0.39
CA2 P00918 2/20 0.37
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CYP2C9 P11712 1/20 0.37
CA4 P22748 1/20 0.37
CA6 P23280 1/20 0.37
CA5A P35218 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3225202 0.85 ESR1 (0.45) CYP3A4ALOX15CASP1CASP7SMN1; SMN2
SCHEMBL10686605 0.85 ESR1 (0.45) CYP3A4ALOX15CASP1CASP7SMN1; SMN2
SCHEMBL70170 0.83 TSHR (0.50) CYP3A4ALOX15CASP1CASP7SMN1; SMN2
SCHEMBL895143 0.83 CYP3A4 (0.47) CYP3A4ALOX15CASP1CASP7SMN1; SMN2
SCHEMBL4706664 0.81 CYP3A4 (0.45) CYP3A4ALOX15CASP1CASP7SMN1; SMN2
Methane SCHEMBL27563519 0.81 TSHR (0.48) CYP3A4ALOX15CASP1CASP7SMN1; SMN2
Water SCHEMBL7548765 0.81 TSHR (0.48) CYP3A4ALOX15CASP1CASP7SMN1; SMN2
Bromide SCHEMBL15303887 0.81 TSHR (0.48) CYP3A4ALOX15CASP1CASP7SMN1; SMN2
Fluoride SCHEMBL7548973 0.81 TSHR (0.48) CYP3A4ALOX15CASP1CASP7SMN1; SMN2
Hydrochloric Acid SCHEMBL2860732 0.81 TSHR (0.48) CYP3A4ALOX15CASP1CASP7SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2033324-B1 MEMBRANES AND METHODS FOR THEIR PREPARATION UNIV BEN GURION (IL) 2016-04-13 EP disclosed
EP-1909142-B1 PHOTOSENSITIVE RESIN COMPOSITION AND ADHESION ENHANCER TORAY INDUSTRIES (JP) 2015-06-24 EP disclosed
US-8710109-B2 Chemically resistant membranes, coatings and films and methods for their preparation BEN GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY (IL) 2014-04-29 US disclosed
US-20130203873-A1 CHEMICALLY RESISTANT MEMBRANES, COATINGS AND FILMS AND METHODS FOR THEIR PREPARATION BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY LTD. (IL) 2013-08-08 US disclosed
US-8455557-B2 Membranes, coatings and films and methods for their preparation BEN GURION UNIVERSITY OF THE NEGEV R&D AUTHORITY (IL) 2013-06-04 US disclosed
US-20120178834-A1 Membranes, Coatings and Films and Methods for Their Preparation BEN GURION UNIVERSITY OF THE NEGEV R&D AUTHORITY (IL) 2012-07-12 US disclosed
US-7977028-B2 Photosensitive resin composition and adhesion promoter TORAY INDUSTRIES, INC. (JP) 2011-07-12 US disclosed
WO-2010095139-A1 CHEMICALLY RESISTANT MEMBRANES, COATINGS AND FILMS AND METHODS FOR THEIR PREPARATION BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY (IL) 2010-08-26 WO disclosed
US-20090123867-A1 PHOTOSENSITIVE RESIN COMPOSITION AND ADHESION PROMOTER TORAY INDUSTRIES, INC. (JP) 2009-05-14 US disclosed
EP-2033324-A2 MEMBRANES, COATINGS AND FILMS AND METHODS FOR THEIR PREPARATION Ben Gurion University of the Negev Research and Development Authority (IL) 2009-03-11 EP disclosed
EP-1909142-A1 PHOTOSENSITIVE RESIN COMPOSITION AND ADHESION ENHANCER TORAY INDUSTRIES, INC. (JP) 2008-04-09 EP disclosed
WO-2007135689-A2 MEMBRANES, COATINGS AND FILMS AND METHODS FOR THEIR PREPARATION BEN GURION UNIVERSITY OF THE NEGEV R&D AUTHORITY (IL) 2007-11-29 WO disclosed
US-6316170-B2 COATING, EXPOSURE, DEVELOPMENT AND HEAT TREATMENT KABUSHIKI KAISHA TOSHIBA (JP) 2001-11-13 US disclosed
US-20010006767-A1 Developing solution and method of forming polyimide pattern by using the developing solution YOSHIAKI KAWAMONZEN 2001-07-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090123867-A1 PHOTOSENSITIVE RESIN COMPOSITION AND ADHESION PROMOTER PCNA, TERB1, SMC2 CYP3A4 4337/4885ALOX15 919/4885CASP1 4666/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.