Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24978306 | 0.84 | ADORA2A (0.35) | ADORA2AADORA1 | |
| SCHEMBL29056885 | 0.81 | — | — | |
| SCHEMBL21963174 | 0.77 | BACE1 (0.30) | — | |
| SCHEMBL21962514 | 0.74 | — | — | |
| SCHEMBL21963068 | 0.73 | — | — | |
| SCHEMBL22021177 | 0.73 | — | — | |
| SCHEMBL24979080 | 0.73 | NLRP3 (0.44) | — | |
| SCHEMBL22021183 | 0.73 | ADORA2A (0.36) | ADORA2AADORA1 | |
| SCHEMBL22021180 | 0.73 | ADORA2A (0.36) | ADORA2AADORA1 | |
| SCHEMBL20699033 | 0.72 | NLRP3 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102096-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS INFLAMMASOME RESEARCH, INC. (US) | 2020-05-22 | — | — | WO | disclosed |