Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 5/20 | 0.41 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.36 |
| ▸ | KLK7 | P49862 | 1/20 | 0.36 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.36 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALB | P02768 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29521888 | 0.92 | ALB (0.44) | TLR2TLR1KMT2AMDM2KLK7 | |
| SCHEMBL21963478 | 0.90 | MDM2 (0.42) | TLR2TLR1MDM2SIRT2SIRT1 | |
| SCHEMBL21963477 | 0.90 | MDM2 (0.42) | TLR2TLR1MDM2SIRT2SIRT1 | |
| SCHEMBL22021494 | 0.90 | MDM2 (0.44) | TLR2TLR1KMT2AMDM2SIRT2 | |
| SCHEMBL22022022 | 0.89 | TLR2 (0.41) | TLR2TLR1SIRT2SIRT1SIRT3 | |
| SCHEMBL29521884 | 0.86 | TLR2 (0.41) | TLR2TLR1MDM2SIRT2ALB | |
| SCHEMBL29521438 | 0.85 | KLK7 (0.49) | TLR2TLR1KMT2AKLK7KLK5 | |
| SCHEMBL24193187 | 0.84 | MDM2 (0.42) | TLR2TLR1KMT2AMDM2 | |
| SCHEMBL31298693 | 0.84 | ALB (0.48) | TLR2TLR1ALB | |
| SCHEMBL24192954 | 0.83 | ALB (0.42) | KMT2ASIRT2SIRT1SIRT3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102348-A1 | THIOAMIDE-CONTAINING COMPOSITIONS AND METHODS OF USE THEREOF | DIMAGNO STEPHEN (US) | 2020-05-22 | — | — | WO | disclosed |