Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.65 |
| ▸ | MAPT | P10636 | 6/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22022114 | 0.93 | NPC1 (0.57) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL21963302 | 0.88 | LMNA (0.59) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL22021343 | 0.87 | LMNA (0.49) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL22021733 | 0.82 | LMNA (0.47) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL19924300 | 0.81 | NPC1 (0.52) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL15306485 | 0.81 | KMT2A (0.56) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL19941889 | 0.80 | POLB (0.52) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL8781730 | 0.77 | LMNA (0.57) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL21963292 | 0.75 | LMNA (0.44) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL4326710 | 0.74 | SMN1; SMN2 (0.58) | MAPTALDH1A1KMT2AHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102348-A1 | THIOAMIDE-CONTAINING COMPOSITIONS AND METHODS OF USE THEREOF | DIMAGNO STEPHEN (US) | 2020-05-22 | — | — | WO | disclosed |