SCHEMBL22022656

SCHEMBL22022656

NCCC[C@H](NC(=O)[C@H](Cc1ccc(Cl)cc1)NC(=O)Nc1ccc2c(CN3CCCC3)cn(Cc3c(Cl)cccc3Cl)c2c1)C(=O)NCCN1CCOCC1

nearest known ligand 0.86

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ F2R P25116 20/20 0.86
▸ F2 P00734 2/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14583983 0.86 F2R (0.82) F2RF2
SCHEMBL4263176 0.81 F2R (0.85) F2RF2
SCHEMBL14583978 0.80 F2R (0.77) F2RF2
SCHEMBL13945253 0.79 F2R (0.74) F2RF2
SCHEMBL12340158 0.77 F2R (0.65) F2RF2
SCHEMBL12340126 0.75 F2R (0.63) F2RF2
SCHEMBL12340155 0.74 F2R (0.67) F2RF2
SCHEMBL14583992 0.73 F2R (0.67) F2RF2
SCHEMBL14090284 0.73 F2R (0.76) F2RF2
SCHEMBL12340129 0.73 F2R (0.65) F2RF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2594318-B1 METHODS OF FACILITATING CELL SURVIVAL USING NEUROTROPHIN MIMETICS UNIV NORTH CAROLINA CHAPEL HILL (US) 2020-06-10 — — EP disclosed
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